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AI-powered genome sequencing benchmarking on Dell infrastructure

Client: Dell Technologies | Solution: Dell PowerEdge XE9680 and XE7740 servers AI-powered genomics benchmarking

Benchmarking AI Infrastructure for Genome Sequencing Workloads

Modern genome sequencing generates vast, high-dimensional datasets demanding exceptional computational and storage performance. However, traditional CPU-only or single-GPU systems struggled to meet the computational demands of sequence alignment, variant calling, and genomic analytics, which led to longer processing times, limited scalability, and inefficient resource use. 

Solution 

Calsoft built an end-to-end AI genome sequencing platform, benchmarked on Dell PowerEdge XE9680/XE7740 with Intel Gaudi accelerators across real-world workloads.

Optimized workload-to-hardware alignment ensured balanced compute, memory, and I/O, improving scalability, minimizing bottlenecks, and sustaining performance.

A four-pillar workload architecture enabled an intelligent pipeline from sequence interpretation to clinical prognosis.

  • Developed a genome sequencing model for accurate and scalable genome sequence prediction. 

  • Implemented a 3D protein structure prediction model to accelerate high-fidelity protein structure prediction.  

  • Enabled protein structure visualization model for structural biology analysis 

  • Built prognostics models for cancer stage and treatment prediction 

Business Value

Background
Operational efficiency
Operational efficiency
Handles high workloads with consistent performance
High accuracy
High accuracy
Delivers precise and stable results
Reliability
Reliability
Maintains performance for small batches and deep networks
High throughput
High throughput
Deliver exceptional throughput for complex genomics 
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AI-Powered Genome Sequencing Benchmarking on Dell Infrastructure